The research interests of the Rose lab are centered on the structure, function and metabolism of plant cell walls and their pivotal roles in growth, development and interactions with pathogens. Additionally, cellulosic cell walls represent a central component of the biofuels industry, as well as providing the building blocks for a broad range of plant-derived products.
The Rose research group has been developing a suite of functional genomics and proteomics tools to advance cell wall research; identifying and characterizing novel cell wall proteins with diverse and currently unknown and unexploited functions. We are now developing a more comprehensive catalog and functional inventory of the plant cell wall proteome, or secretome, using fruit development and ripening, and potential bioenergy crops and two key experimental systems. Our lab is also heavily invested in sustainable biofuels research, developing analytic methods for profiling wall composition and bioethanol potential of diverse feedstocks. We are taking a lead role in coordinating biofuels research among Cornell plant scientists.
- Yeats, T. H., Martin, L. B., Viart, H. M., Isaacson, T., He, Y., Zhao, L., Matas, A. J., Buda, G. B., Domozych, D. S., Clausen, M. H., & Rose, J. (2012). The identification of cutin synthase: formation of the plant polyester cutin. Nature Chemical Biology. 8:609-611.
- Zhang, S., Sherwood, R. W., Yang, Y., Fish, T., Chen, W., McCardle, J. A., Jones, R. M., Yusibov, V., May, E., Rose, J., & Thannhauser, T. W. (2012). Comparative characterization of the glycosylation profiles of an influenza hemagglutinin produced in plant and insect hosts. Proteomics. 12:1269-88.
- Harris, D. M., Corbin, K., Wang, T., Gutierrez, R., Bertolo, A., Petti, C., Smilgies, D. M., Estevez, J. M., Bonetta, D., Urbanowicz, B. R., Ehrhardt, D. W., Somerville, C., Rose, J., Hong, M., & DebBolt, S. (2012). Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1A903V and CESA3T942I . Proceedings of the National Academy of Sciences of the United States of America. 109:4098-103.
- Lopez-Casado, G., Covey, P. A., Bedinger, P. A., Mueller, L. A., Thannhauser, T. W., Zhang, S., Fei, Z., Giovannoni, J. J., & Rose, J. (2012). Enabling proteomic studies with RNA-Seq: the proteome of tomato pollen as a test case. Proteomics. 12:761-774.
- Yeats, T. H., Buda, G. J., Wang, Z., Chehanovsky, N., Moyle, L. C., Jetter, R., Schaffer, A. A., & Rose, J. (2012). The fruit cuticles of wild tomato species exhibit architectural and chemical diversity, providing a new model for studying the evolution of cuticle function. The Plant Journal. 69:655–666.
- Lee, S. J., & Rose, J. (2011). A yeast secretion trap assay for identification of secreted proteins from eukaryotic phytopathogens and their plant hosts. Methods in Molecular Biology. 835:519-530.
- Bedinger, P. A., Chetelat, R., McClure, B., Moyle, L. C., Rose, J., Stack, S., Van der Knaap, E., Baek, Y. S., Lopez-Casado, G., Covey, P. A., Kumar, A., Li, W., Nunez, R., Cruz-Garcia, F., & Royer, S. (2011). Interspecific reproductive barriers in the tomato clade: opportunities to decipher mechanisms of reproductive isolation . Sexual Plant Reproduction. 24:171-187.
- Centeno, D., Osorio, S., Nunes-Nesi, A., Bertolo, A. L., Carneiro, R. T., Araujo, W. L., Steinhauser, M. C., Michalska, R., Rohrmann, J., Geigenberger, P., Oliver, S., Stitt, M., Carrari, F., Rose, J., & Fernie, A. R. (2011). Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. The Plant Cell. 23:162-184.
Presentations and Activities
- Peeling apart the structural and functional complexity of the cuticularized plant cell wall. February 2012. DOE. Washington DC.
- Tissue and cell type specific transcriptome profiling of tomato fruit provides insights into metabolic and regulatory specialization?. 2012. Advanced Technology Seminar Series. Cornell.
- Multilayered strategies for attack, defense and counter-defense in the plant cell wall: the infection of tomato by Phytophthora infestans as a model system. 2011. Annual Tomato Disease Workshop. Ithaca, NY.