Senior Research Associate/Senior Lecturer
Giulia Friso obtained her B.Sc. and M.Sc. in Biology and her Ph.D in Biochemistry and Biophysics at the University of Padua (Italy). She was a post-doctoral fellow at the Department of Biochemistry at Imperial College, London (U.K.), and at the Department of Pharmaceutical Chemistry at U.C.S.F. in San Francisco. She also was a research scientist at the discovery unit of the Pharmaceutical Company AstraZeneca in Stockholm (Sweden). Giulia joined the Plant Biology Department at Cornell University in 2001, and is currently senior research associate and senior lecturer.<br>
My current professional objective is to excel in mass spectrometry and the bioinformatics pipeline of data analyses applied to plant biology and in supervising, advising and training of others in the academic environment. I aim to work as close to the cutting edge of mass spectrometry, biochemistry, and bioinformatics and to follow and implement new developments and tools in plant biology. In that context I aim to be productive and contribute to efforts in obtaining federal funding.
Outreach and Extension Focus
Take a tour of the medicinal plants section of the Cornell Botanic garden with me and Pamela Shade by clicking the link below:<br><br><a href="https://www.youtube.com/watch?v=LwLiPAOHC5I&feature=youtu.be">https://www.youtube.com/watch?v=LwLiPAOHC5I&feature=youtu.be</a><br><br><br><br><br><br><br>
Listen to my Podcast interview on Ethnobotany "Nature's prescription" from the Cornell series State of the pod, below:<br><br>"http://www.stateofthepod.com/2019/12/06/natures-prescription/">http://www.stateofthepod.com/2019/12/06/natures-prescription/
In 2018 Giulia received an Engaged opportunity grant from Engaged Cornell: “Connecting Cornell Students to the Cayuga Nation – Hosting the Cayuga Nation Chief Sam George to further the relationship between Cornell students and local indigenous people”
2016 Faculty Institute on Community-Engaged Learning and Teaching (CELT) 2016 Institute and scholarship, C.U.
2016 Faculty Institute for Diversity, C.U.
2016 Global Learning Institute and workshops, C.U.
2017 Group Work Institute, C.U.
2018 Flipping the classroom workshop, C.U.
My goal as a teacher is to inspire my students in the learning process, and engage them in the process of discovery, facilitate mastery of plant biology, help them integrate concepts of biochemistry, pharmacology, physiology, ethnobotany, indigenous knowledge and bioprospecting. I also aim to transmit my enthusiasm as a researcher and a teacher influencing my students to commit to my course and interest them in the field of medicinal plants and drug discovery. I am deeply interested to convey a knowledge and awareness of different cultural practices, values, and beliefs, and help my students gain an understanding of their own cultural perspective.<br>I teach two courses on medicinal plants, which I developed in 2016, prerequisite for the Plant and Human Health concentration of the Plant Science major. Medical Ethnobotany (3 credits course, 2000 level) exposes students to the relationship between plants and native people in various parts of the world, their effect on human health and their mechanism of action in the human bodies. I also teach Medicinal Botany and Drug Discovery (2 credits, 3000 level).<br>Plants have been used for the maintenance of health and source of medicinal agents for thousands of years and a remarkable number of modern drugs have been isolated or derived from plants. In this course, we explore the mechanisms of action, the effects, efficacy and potency of isolated bio-active compounds found in injurious, hallucinogenic and medicinal plants as source of medicines, sold by pharmaceutical companies. During the course of the semester we introduce 12 case studies from 12 different plant species. Furthermore, the course cover the distribution of plant secondary metabolites, the use of techniques in the isolation and structure elucidation of natural products, their pharmacokinetic properties and the steps involved in drug production and approval.<br><br>In the summer and winter semester Giulia offers an online version of PLBIO2100 Medical Ethnobotany through the Cornell School of Continuing Education Online Learning.<br><br>Giulia recently developed an eCornell Professional Certificate Program on the theme of Plants and Health open to individuals and organizations around the world and offered multiple times per year. The certificate will be launched in the fall of 2020 and will include 6 individual courses on the theme of plant and health.
- Friso, G. (2020). In Vivo Trapping of Proteins Interacting with the Chloroplast CLPC1 Chaperone: Potential Substrates and Adaptors. Montandon C,<b> Friso G</b>, Liao JR, Choi J, van Wijk KJ.J Proteome Res. 2019 Jun 7;18(6):2585-2600.
- Bhuiyan, N. H., Friso, G., Rowland, E., Majsec, K., & van Wijk, K. (2016). The Plastoglobule-Localized Metallopeptidase PGM48 Is a Positive Regulator of Senescence in Arabidopsis thaliana. The Plant Cell. 28:3020-3037.
- Lohscheider, J. N., Friso, G., & van Wijk, K. (2016). Phosphorylation of plastoglobular proteins in Arabidopsis thaliana. JXB: Journal of Experimental Botany. 67:3975-3984.
- Bhuiyan, N. H., Friso, G., Poliakov , A., Ponnala , L., & van Wijk, K. (2015). MET1 Is a Thylakoid-Associated TPR Protein Involved in Photosystem II Supercomplex Formation and Repair in Arabidopsis. The Plant Cell.
- Friso, G., & van Wijk, K. (2015). Posttranslational Protein Modifications in Plant Metabolism. Plant Physiology.
- , J., & Friso, G. (2015). Structures, Functions, and Interactions of ClpT1 and ClpT2 in the Clp Protease System of Arabidopsis Chloroplasts. The Plant Cell.
- van Wijk, K., Friso, G., Walther , D., & Schulze, W. X. (2014). Meta-Analysis of Arabidopsis thaliana Phospho-Proteomics Data Reveals Compartmentalization of Phosphorylation Motifs. The Plant Cell. 26:2367Ð2389.
- Friso, G., Majeran, W., Huang, M., Sun, Q., & van Wijk, K. (2010). Reconstruction of metabolic pathways, protein expression and homeostasis machineries across maize bundle sheath and mesophyll chloroplasts; large scale quantitative proteomics using the first maize genome assembly. Plant Physiology. 152:1219-1250.
- Kroeger, T. S., Watkins, K. P., Friso, G., van Wijk, K., & Barkan, A. (2009). A plant-specific RNA binding domain revealed through analysis of chloroplast group II intron splicing. PNAS: Proceedings of the National Academy of Sciences of the United States of America. 106:4537-42.
- Sun, Q., Zybailov, B., Majeran, W., Friso, G., Olinares, P. B., & van Wijk, K. (2009). PPDB, the Plant Proteomics Database at Cornell. Nucleic Acids Research. 37:D969-74.
Presentations and Activities
- A high resolution structural and proteomic atlas of the developing rice leaf. 60th ASMS Conference on Mass Spectrometry and Allied Topics . May 2012. ASMS. Vancouver, Canada.