Jian Hua studied biology at Fudan University, Chinese Academy of Science, and Caltech and did postdoc at MIT before coming to Cornell. She studies molecular genetics of plant responses to environmental signals.
My long-term goal is to understand the molecular mechanisms underlying how plants respond to temperature variations to regulate their development and immunity. Proper responses to environmental signals are essential for their optimal growth, reproduction, and fitness. Understanding their molecular basis not only is fundamental to the central biological question of signal transduction and integration, but also better prepares us for global climate changes.
Research programs in my lab have evolved from the study of growth homeostasis at varying temperatures in Arabidopsis to studies of 1) temperature regulation of plant growth, 2) regulation of plant immunity, and 3) interplay between temperature and immunity. We use induced mutations to dissect signaling pathways as well as natural variations to reveal adaptive changes in signaling. We aim at a deeper understanding of how plants adapt and evolve in a change environment.
I teach plant development, plant genetics, plant molecular biology laboratory, undergraduate biology research, and graduate level modules.
- Wang, S., Bai, G., Wang, S., Yang, L., Yang, F., Wang, Y., Jian-Kang, Z., & Hua, J. (2016). Chloroplast RNA-Binding protein RBD1 promotes chilling tolerance through 23S rRNA processing in Arabidopsis. PLoS Genetics. 12:e1006027.
- Zhilong Bao,, Hua, J., & , (2015). Linking cell cycle with innate immunity in Arabidopsis. Molecular Plant. 8:980-982.
- Gou, M., Zhang, Z., Zhang, N., Huang, Q., Monaghan, J., Yang, H., Shi, Z., Zipfel, C., & Hua, J. (2015). Opposing effects on two phases of defense responses from concerted actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis. Plant Physiology. 169:2304-2323.
- Bao, Z., Zhang, N., & Hua, J. (2014). Endopolyploidization and flowering time are antagonistically regulated by checkpoint component MAD1 and immunity modulator MOS1. Nature communications. 5:5628.
- Zou, B., Yang, D., Shi, Z., Dong, H., Hua, J., & , (2014). Monoubiquitination of Histone 2B at the disease resistance gene locus regulates its expression and impacts immune responses in Arabidopsis. Plant Physiology. 165:309.
- Hua, J. (2013). Modulation of plant immunity by light, circadian rhythm, and temperature. Current Opinion in Plant Biology. 16:406-413.
- Bao, Z., Yang, H., & Hua, J. (2013). Perturbation of cell cycle regulation triggers plant immune response via activation of disease resistance genes. Proceedings of the National Academy of Sciences of the United States of America. 110:2407-12.
- Zhu, Y., Du, B., Qian, J., Zou, B., & Hua, J. (2013). Disease resistance gene-induced growth inhibition is enhanced by rcd1 independent of defense activation in Arabidopsis. Plant Physiology. 161:2005-13.
- Mang, H., Qian, W., Zhu, Y., Qian, J., Kang, H., Klessig, D. F., & Hua, J. (2012). ABA deficiency antagonizes high temperature inhibition of disease resistance through enhancing nuclear accumulation of R proteins SNC1 and RPS4. Plant Cell. 24:1271-1284.
- Zhu, Y., Mang, H., Sun, Q., Hipps, A., & Hua, J. (2012). Gene discovery using mutagen-induced polymorphisms and deep sequencing: application to plant disease resistance. Genetics. 192:139-146.