Jian Hua had education in biology at Fudan University, Chinese Academy of Science, and Caltech. She did postdoctoral research at MIT before joining faculty at Cornell. Her lab investigates molecular genetic mechanisms of environmental responses in plants.
My long-term goal is to understand the molecular mechanisms underlying how plants respond to temperature variations to regulate their development and immunity. Proper responses to environmental signals are essential for their optimal growth, reproduction, and fitness. Understanding their molecular basis not only is fundamental to the central biological question of signaling and adaptation, but also better prepares us for global climate changes.
Research programs in my lab have evolved from the study of growth homeostasis at varying temperatures in Arabidopsis to studies of 1) temperature regulation of plant growth, 2) regulation of plant immunity, and 3) interplay between temperature and immunity. We use induced mutations to dissect signaling pathways as well as natural variations to reveal adaptive changes in signaling. We aim at a deeper understanding of how plants adapt and evolve in a changing environment.
I teach plant genetics, plant molecular biology and bio-engineering, plant molecular biology laboratory, undergraduate biology research, and graduate level modules.
- Li, Z., Liu, H., Ding, Z., Yan, J., Yu, H., Pan, R., Hu, J., Guan, Y., & Hua, J. (2020). Low temperature enhances plant immunity via salicylic acid pathway genes that are repressed by ethylene. Plant Physiology.
- Yan, J., Yu, H., Li, B., Fan, A., Melkonian, J. J., Wang, X., Zhou, T., & Hua, J. (2019). Cell autonomous and non-autonomous functions of plant intracellular immune receptors in stomatal defense and apoplastic defense. PLoS Pathogens. 15.
- Yang, L., Chen, X., Wang, Z., Sun, Q., Hong, A., Zhang, A., Zhong, X., & Hua, J. (2019). HOS15 and HDA9 negatively regulate immunity through histone deacetylation of intracellular immune receptor NLR genes in Arabidopsis. New Phytologist.
- Wang, Z., Yang, L., Liu, Z., Lu, M., Wang, M., Sun, Q., Lan, Y., Shi, T., Wu, D., & Hua, J. (2019). Natural variations of growth thermo-responsiveness determined by SAUR 26/27/28 proteins in Arabidopsis thaliana. New Phytologist.
- Zhang, N., Wang, Z., Bao, Z., Yang, L., Wu, D., Shu, X., & Hua, J. (2018). MOS 1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis. The Plant Journal. 93:66--78.
- Yin, X., Zou, B., Hong, X., Gao, M., Yang, W., Zhong, X., He, Y., Kuai, P., Lou, Y., Huang, J., Hua, J., & He, Z. (2018). Rice copine genes OsBON1 and OsBON3 function as suppressors of broad-spectrum disease resistance. Plant Biotechnology Journal. 16:1476-1487 .
- Zhang, N., Wang, Z., Bao, Z., Yang, L., Wu, D., Shu, X., & Hua, J. (2017). MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis. The Plant Journal. 93:66-78.
- Yang, D., Shi, Z., Bao, Y., Yan, J., Yang, Z., Yu, H., Li, Y., Gou, M., Wang, S., Zou, B., Xu, D., Ma, Z., Kim, J., & Hua, J. (2017). Calcium pumps and interacting BON1 protein modulate calcium signature, stomatal closure, and plant immunity. Plant Physiology. 175:424–437.
- Wang, S., Bai, G., Wang, S., Yang, L., Yang, F., Wang, Y., Jian-Kang, Z., & Hua, J. (2016). Chloroplast RNA-Binding protein RBD1 promotes chilling tolerance through 23S rRNA processing in Arabidopsis. PLOS Genetics. 12:e1006027.
- Gou, M., Zhang, Z., Zhang, N., Huang, Q., Monaghan, J., Yang, H., Shi, Z., Zipfel, C., & Hua, J. (2015). Opposing effects on two phases of defense responses from concerted actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis. Plant Physiology. 169:2304-2323.